Heart Valve Regeneration

Causes Stimulated Tissues to Release SDF-1 and Follistatin which Causes Stem Cells to Home to Site and Forms New Smooth Muscle.

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Valvublator is designed to help patients keep their own heart valve instead of getting a pig, cow, plastic or steel artificial implant!

Catheter based and non-invasive systems to decalcify and regenerate heart valves with precise bioelectric signaling sequences and precision focused ultrasonic energy.

 

Decalcifies + Cell Sods + Regenerates + Surface Modifies + Strengthens

= Rebuilds heart valve leaflets and orifice utilizing a patient’s own cells.

Full real time optical and echo viewing to guide valve repair.

Embolitic fragment protection throughout procedure.

Combination of:

1. Mechanical burr cleaning with controllable deflecting tip.
2. Ultrasonic cleaning.
3. Biochemical safe solvent cleaning.
4. Vacuum removal of debris.
5. Cell sodding micro needles.
6. Microcurrent regeneration signal = recruits stem cells with homing signal and differentiates them to valve tissue.
7. Spay-on scaffolding for rebuilding highly damaged leaflets.
8. Full optical, ultrasound or echo viewing of valve repair field of view real time.

Degenerative Mitral Stenosis: Unmet Need for Percutaneous Interventions

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Valvublator’s 4 Step Process to Total Heart Valve Regeneration

The future is non-invasive heart valve decalcification and regeneration and Valvublator plans to lead the way!

 

3 stage decalcification cleaning

(1) vibrating burr + (2) ultrasonic + (20 biologically safe solvent (citric acid) all via same guiding catheter.

reduce risk of re-calcification

Treat valve with special spray (confidential composition at this time) on composition following decalcification to reduce risk of re-calcificatio

Regenerate valve by recruiting stem cells

and releasing other regenerative proteins with bioelectric signaling that starts as invasive catheter electrode placements for first treatments and then transitions to non-invasive treatments over a course of about 12 to 20 weeks.

Prevent re-calcification

by monthly @ home stimulation 30 minutes of thigh muscle with non-invasive gel electrodes to release beneficial proteins such as klotho. Our patent pending bioelectric signaling sequences developed at our lab in Utah increase Klotho expression by up to 480%.

New Paradigm = Decalcify and Regenerate Heart Valves BEFORE a cow, pig, plastic, steel or cadaver implant is needed!

We believe our minimally invasive or non-invasive decalcification and regeneration product will be used in the future to decalcify and regenerate heart valves BEFORE they get so diseased that a pig, cow, cadaver, steel or plastic implant is needed. Just like we go to the dentist early now to clean our teeth BEFORE plaque and disease gets too advanced requiring a dental tooth implant.
 

Introducing Valvublator II Simplified Design

Original Valvublator I Design

CAUTION Disclaimer and Warning: Products described on this web site are in early stage development and are not yet proven safe or effective in statistically significant controlled clinical studies. Any statement or phrases implying efficacy or safety in any form are considered modified by “intended to” or “designed to”. Investigational use only in countries where investigation is permitted by law and proper filings have been made and appropriate regulatory clearances have been granted. Any use of the product(s) must be in an authorized clinical study with institutional review board (ethics committee) approval and proper patient consent procedures followed. For other countries product is only available for laboratory investigation by credentialed institutions and investigators with proper clearances with a research agreement in place with a study sponsor. NOT AVAILABLE FOR SALE.